Calexico is a Tucson, Arizona-based Americana/Tex-Mex/indie rock band. The band's two main members, Joey Burns and John Convertino, first played together in Los Angeles as part of the group Giant Sand. They have recorded a number of albums on Quarterstick Records, while their 2005 EP In the Reins recorded with Iron & Wine has reached the Billboard 200 album charts.

Their musical style is influenced by traditional Latin sounds of mariachi, conjunto, cumbia, Tejano music and also the Southwestern United States country music as well as '50s-'60s jazz and '90s-'00s post-rock, and they have been described by some as "desert noir" or indie rock. The band is named for the border town of Calexico, California.